Publications
Henning Stöckmann, Violeta L. Marin, Paul Nimmer, Corina M. Balut, Donald J. Davidson, Paul L. Richardson, Anil Vasudevan Glycan-mediated ligand-controlled click chemistry for small molecule target identification BioChemBio, 2015
Peter Ansell, Haiying Zhang, Don J. Davidson, John E. Harlan, John Xue, Sevan Brodjian, Rick Lesniewski, Evelyn McKeegan Recombinant Kringle 5 from Plaminogen Antagonizes Heptaocyte Growth Factor-Mediated Signaling, Eur. J. of Cancer, 2010 Mar;46(5):966-73.
McFarland BC, Stewart J, Hamza A, Davidson D, Henkin J, and Gladson CL. Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: Sensitization by radiation and requirement for GRP78 and LRP1. Cancer Res, (2009) July 1: 69(13): 5537-5545.
Don J. Davidson, Catherine Haskell, Sandy Majest, Abdullah Kherzai, David A. Egan, Karl A. Walter, Andrew Schneider, Earl J. Gubbins, Larry Solomon, Zhebo Chen, Rick Lesniewski, Jack Henkin Kringle 5 of Human Plasminogen Induces Apoptosis of Endothelial and Tumor Cells Through Surface Expressed GRP78, Cancer Res. 2005 Jun 1;65(11):4663-72.
Fortuna Haviv, Michael F. Bradley, Douglas M. Kalven, Andrew J. Schneider, Donald J. Davidson, Sandra M. Majest, Laura M. McKay, Catherine J. Haskell, Randy L. Bell, Bach Nguyen, Kennan C. Marsh, John T. Uchic, James Ferrero, Yi-Chun Wang, Juan Leal, Rae D. Record, Jason Hodde, Stephen F. Badylak, Richard R. Lesniewski and Jack Henkin Thrombospondin-1 (TSP-1) Mimetic Peptide Inhibitors of Angiogenesis and Tumor Growth: Design, Synthesis and Optimization of Pharmacokinetics and Biological Activities. J Med Chem. 2005 Apr 21;48(8): 2838-46.
Sheppard GS, Kawai M, Craig RA, Davidson DJ, Majest SM, Bell RL, Henkin J Lysyl 4-Aminobenzoic Acid Derivatives as Potent Small Molecule Mimetics of Plasminogen Kringle 5. Bioorg Med Chem Lett. (2004) Feb 23;14(4):965-6
Hajduk PJ, Boyd S, Nettesheim D, Nienaber V, Severin J, Smith R, Davidson D, Rockway T, Fesik SW (2000) Identification of Novel Inhibitors of Urokinase via NMR-based Screening. J Med Chem Oct 19;43(21):3862-6
Nienaber VL, Davidson D, Edalji R, Giranda VL, Klinghofer V, Henkin J, Magdalinos P, Mantei R, Merrick S, Severin JM, Smith RA, Stewart K, Walter K, Wang J, Wendt M, Weitzberg M, Zhao X, Rockway T. (2000) Structure-directed Discovery of Potent Non-peptidic Inhibitors of Human Urokinase that Access a Novel Binding Subsite. Structure Fold Des 2000 May 15;8(5):553-63
Vicki Nienaber, Jieyi Wang, Don Davidson, and Jack Henkin. (1999) Re-engineering of Human Urokinase Provides a System for Structure-based Drug Design at High Resolution and Reveals a Novel Binding Sub-site. The Journal of Biological Chemistry 2000 Mar 10;275(10):7239-48
Yihai Cao, Andrew Chen, Seong Sooa-An, Richard-Weidong Ji, Yumei Cao, Don Davidson, Miguel Llinas. (1997) Kringle 5 of Plasminogen is a Novel Inhibitor of Endothelial Cell Growth. The Journal of Biological Chemistry. 272, (36) p22924-22928.
Yihai Cao, Richard W. Ji, Don Davidson, Johann Schaller, Daniel Marti, Sabine Sohndel, Stephen McCance, Michael S. O’Reilly, Miguel Llinas, and Judah Folkman (1996) Kringle Domains of Human Angiostatin. The Journal of Biological Chemistry 271, (46) p29461-29467
Sandra E. Burke, Don J. Davidson, Nathan L. Lubbers, Irene M. Reininger and Jack Henkin (1996) Differential Effects of LYS- and MINI- Plasminogen on clot Lysis Induced by Recombinant Urokinase and Recombinant Pro-Urokinase in a Canine Thrombosis Model. Thrombosis Research, 83 (6) p 421-431
Rabbani SA, Harakidas P, Davidson DJ, Henkin J, Mazar AP (1995) Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA). Int J Cancer, 63(6):840-5.
Davidson, D.J., Castellino, F.J. (1993) The Influence of the Nature of Asparagine 289-linked Oligosaccharide on the Activation by Urokinase and Lysine Binding Properties of Natural and Recombinant Human Plasminogens. Journal of Clinical Investigation, 92 (1), p249-254.
Castellino, F.J., Davidson, D.J., Rosen, E., McLinden, J. (1993) Expression of Human Plasminogen cDNA in Lepidopteran Insect Cells and Analysis of Asparagine-linked Glycosylation Patterns of Recombinant Plasminogens. Methods in Enzymology, 223, p168-185.
Radek, J.T., Davidson, D.J., and Castellino, F.J. (1993) Streptokinase-Plasmin(ogen) Activator Assays. Methods in Enzymology 223, p145-155.
Davidson, D.J., Bretthauer, R.K., Castellino, F.J. (1991) alpha-Mannosidase-catalyzed Trimming of High-mannose Glycans in Noninfected and Baculovirus-infected Spodoptera frugiperda Cells(IPLB-SF-21-AE). A Possible Contributing Reulatory Mechanism for Assembly of Complex-type Oligosaccharides in Infected Cells. Biochemistry, 30 (41) p9811-9815.
Davidson, D.J., & Castellino, F.J. (1991). Asparagine-linked Oligosaccharide Processing in Lepidoptern Insect Cells Temporal Dependence of the Nature of Oligosaccharide Assembled on Asparagine289of Recombinant Human Plasminogen Produced in Baculovirus-infected Spodoptera frugiperda (IPLB-SF-21AE) Cells. Biochemistry 30, Accelerated publication, 6165-6174.
Davidson, D.J., & Castellino, F.J. (1991). The Structures of the Asn289- linked Oligosaccharides Assembled on Recombinant Human Plasminogen Expressed in a Mamestra brassicae Cell Line (IZD-MBO 503) Biochemistry 30, 6689-6696.
Ghosh, S., Lee, S.M., Brown, T., Basu, M., Hawes, J., Davidson, D., Basu, S. (1991). Use of Exoglycosidases from Venus mercenaria (freshwater clam) as a Tool for Structural Studies of GlycosphingoLipids and Glycoproteins. Analytical Biochemistry 196, 252-261.
Hink, W.F., Thomsen, D.R., Davidson, D.J., Meyer, A.L., & Castellino, F.J. (1991) Expression of Three Recombinant Proteins Using Baculovirus Vectors in Twenty-Three Insect Cell Lines. BioTechnology Progress 7, 9-14.
Davidson, D.J., & Castellino, F.J. (1991). Oligosaccharide Structures Present on Asparagine289 of Recombinant Human Plasminogen Expressed in Chinese Hamster Ovary Cell Line. Biochemistry 30: 625-633.
Davidson, D.J., Fraser, M.J., & Castellino, F.J.(1990). Oligosaccharide Processing in the Expression of Human Plasminogen cDNA by Lepidoptern Insect (Spodoptera frugiperda) Cells. Biochemistry 29: 5584-5590.
Davidson, D.J., Higgins, D.L., & Castellino, F.J. (1990). Plasminogen Activator Activities of Equimolar Complexes of Streptokinase with Variant Recombinant Plasminogen Biochemistry 29: 3585-3590.